{"product_id":"entresto-tablets-brand-name","title":"ENTRESTO Tablets 50mg \/ 100mg \/ 200mg [Brand Name]","description":"\u003cdiv\u003e\n\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong\u003e\u003cem\u003eATTENTION\u003c\/em\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong\u003ePlease check countries we ship currently at the following URL \u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\u003ca href=\"https:\/\/zen-pharmacy-japan.com\/pages\/countries-we-ship-currently\" title=\"Countries we ship currently\" target=\"_blank\"\u003ehttps:\/\/zen-pharmacy-japan.com\/pages\/countries-we-ship-currently\u003c\/a\u003e\u003cbr\u003e\u003cstrong style=\"color: #0000ff;\"\u003ePlease read \"Drug Information\" for your strength before purchase.\u003c\/strong\u003e\u003cbr\u003e\u003cdiv class=\"zen-di-row\" style=\"display:flex;flex-wrap:wrap;gap:8px;margin:10px 0 14px;\"\u003e\n\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0011\/1689\/7343\/files\/Entresto_Tablets_50_mg.pdf?v=1719901706\" title=\"Drug Information 50mg (PDF)\" rel=\"noopener\" target=\"_blank\" style=\"flex:1 1 46%;display:flex;align-items:center;justify-content:center;gap:6px;white-space:nowrap;background:#3d4fb5;color:#ffffff;font-weight:700;text-decoration:none;padding:11px 6px;border-radius:4px;font-size:13px;line-height:1.2;\"\u003e▶ Drug Information \u003cspan style=\"background:#ffffff;color:#3d4fb5;border-radius:3px;padding:1px 7px;font-size:13px;\"\u003e50mg\u003c\/span\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0011\/1689\/7343\/files\/Entresto_Tablets_100_mg.pdf?v=1719758854\" title=\"Drug Information 100mg (PDF)\" rel=\"noopener\" target=\"_blank\" style=\"flex:1 1 46%;display:flex;align-items:center;justify-content:center;gap:6px;white-space:nowrap;background:#3d4fb5;color:#ffffff;font-weight:700;text-decoration:none;padding:11px 6px;border-radius:4px;font-size:13px;line-height:1.2;\"\u003e▶ Drug Information \u003cspan style=\"background:#ffffff;color:#3d4fb5;border-radius:3px;padding:1px 7px;font-size:13px;\"\u003e100mg\u003c\/span\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0011\/1689\/7343\/files\/Entresto_Tablets_200_mg.pdf?v=1719903421\" title=\"Drug Information 200mg (PDF)\" rel=\"noopener\" target=\"_blank\" style=\"flex:1 1 46%;display:flex;align-items:center;justify-content:center;gap:6px;white-space:nowrap;background:#3d4fb5;color:#ffffff;font-weight:700;text-decoration:none;padding:11px 6px;border-radius:4px;font-size:13px;line-height:1.2;\"\u003e▶ Drug Information \u003cspan style=\"background:#ffffff;color:#3d4fb5;border-radius:3px;padding:1px 7px;font-size:13px;\"\u003e200mg\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eActive ingredient\u003c\/strong\u003e\u003cbr\u003eSacubitril valsartan sodium hydrate\u003cbr\u003e\u003cstrong\u003e\u003cspan style=\"color: #ff0000;\"\u003eBrand name medicine\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003eENTRESTO \u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eEffects of this medicine\u003c\/strong\u003e\u003cbr\u003e・This medicine suppresses the actions of substances called neprilysin and angiotensin II to lower blood pressure. It also reduces the amount of water stored in the body, reduces the burden on the heart, and prevents worsening of heart failure.\u003cbr\u003e・It is usually used to treat chronic heart failure and hypertension.\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eDosing schedule (How to take this medicine)\u003c\/strong\u003e\u003cbr\u003e・For chronic heart failure:\u003cbr\u003e・This product is available in 50mg, 100mg and 200mg tablets. Select the strength prescribed by your doctor from the options above.\u003cbr\u003e・[for adults] In general, for adults, take 50 mg of sacubitril valsartan at a time, twice a day as the initial dose. The dosage may be increased up to 200 mg at intervals of 2 to 4 weeks in a stepwise manner if the adverse reactions do not interfere with the treatment. ・The dose is 50 mg, 100 mg or 200 mg at a time. The dosage may be adjusted according to the tolerability.\u003cbr\u003e・[for children] In general, for children aged 1 year or older, take sacubitril valsartan at the starting dose based on body weight (details are described below) twice daily. If tolerated, the dose may be gradually increased to the target dose at 2 to 4 weeks intervals. The dosage may be adjusted according to tolerability.\u003cbr\u003e・=Details of dosage for children (single dose)=\u003cbr\u003e・The starting dose per administration based on body weight is 0.8 mg\/kg for under 40 kg, 0.8 mg\/kg for 40 kg or over but under 50 kg, and 50 mg for over 50 kg. The first ascending dose will be 1.6 mg\/kg for under 40 kg, 50 mg for 40 kg or over but under 50 kg, and 100 mg for over 50 kg. The second ascending dose will be 2.3 mg\/kg for under 40 kg, 100 mg for 40 kg or over but under 50 kg, and 150 mg for over 50 kg. The target dose is 3.1 mg\/kg for under 40 kg, 150 mg for 40 kg or over but under 50 kg, and 200 mg for over 50 kg.\u003cbr\u003e・The starting dose may be started with the first ascending dose depending on your previous treatment history and condition.\u003cbr\u003e・*For Children, prepared syrup (suspension) may be given.\u003cbr\u003e・For hypertension: In general, for adults, take 200 mg of sacubitril valsartan at a time, once a day. The dosage should be adjusted according to the age or symptoms. The maximum dose is up to 400 mg at a time, once a day.\u003cbr\u003e・In any case, strictly follow the instructions.\u003cbr\u003e・The initial dose may be started at 100 mg once daily for the treatment of hypertension depending on your condition.\u003cbr\u003e・If you miss a dose, take a dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eBefore using this medicine, be sure to tell your doctor and pharmacist\u003c\/strong\u003e\u003cbr\u003e・If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods.\u003cbr\u003e・If you have renal artery stenosis, hyperkalemia,cerebrovascular disorder, renal dysfunction, hepatic dysfunction, hypotension, a history of angioedema, or schedule of surgery.\u003cbr\u003e・If you are on hemodialysis or a regimen of low-salt diet.\u003cbr\u003e・If you are pregnant, possibly pregnant or breastfeeding.\u003cbr\u003e・If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003ePrecautions while taking this medicine\u003c\/strong\u003e\u003cbr\u003e・This medicine may cause dizziness or lightheadedness. Pay close attention when you work at heights, drive a car or operate machinery.\u003cbr\u003e・This medicine has been reported to be teratogenic (may cause malformations in fetuses), women of childbearing potential should avoid pregnancy by using a reliable contraceptive method while using this medicine and for 1 week after the discontinuation of this medicine. So if you suspect that you are pregnant, contact your doctor immediately.\u003cbr\u003e・It is recommended not to breastfeed while taking this medicine. If you are breastfeeding, consult with your doctor.\u003cbr\u003e・For healthcare professional use only\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eStorage conditions and other information\u003c\/strong\u003e\u003cbr\u003e・Keep out of the reach of children. Store away from direct sunlight, heat and moisture.\u003cbr\u003e・Discard the remainder. Do not store them. If you are not sure how to discard, consult with your pharmacist or medical institution. Do not give it to anyone else.\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eProduct Overview\u003c\/strong\u003e\u003cbr\u003eENTRESTO (sacubitril valsartan sodium hydrate) is a Japanese prescription medicine used to treat chronic heart failure and hypertension. The Japanese product is manufactured under Japanese GMP and supplied in PTP sheets of 10 tablets with Japanese labeling.\u003cbr\u003e\u003cbr\u003eAvailable on this page: 50mg \/ 100mg \/ 200mg. Select the strength and quantity from the options above. All strengths are the genuine Japanese product dispensed and shipped with tracking from our licensed pharmacy in Japan.\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eFrequently Asked Questions\u003c\/strong\u003e\u003cbr\u003e\u003cb\u003eQ. What is the difference between the different strengths?\u003c\/b\u003e\u003cbr\u003eThe only difference is the amount of sacubitril valsartan sodium hydrate per tablet. All strengths are the same ENTRESTO product with the same indication. Please choose the strength your doctor prescribed; do not change strength without medical advice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQ. How many tablets are in one order?\u003c\/b\u003e\u003cbr\u003eOptions: 1 sheet (10 tablets) \/ 10 sheets (100 tablets).\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQ. Do I need a prescription to order?\u003c\/b\u003e\u003cbr\u003eENTRESTO is a prescription medicine in Japan. Please order only for personal use in accordance with the import regulations of your country, and consult your doctor before use.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQ. Which countries do you ship to?\u003c\/b\u003e\u003cbr\u003ePlease see our \u003ca href=\"https:\/\/zen-pharmacy-japan.com\/pages\/countries-we-ship-currently\"\u003eshipping countries page\u003c\/a\u003e. Orders over JPY 50,000 ship free.\u003cbr\u003e\u003cbr\u003e\n\u003c\/div\u003e","brand":"ZEN PHARMACY JAPAN","offers":[{"title":"50mg \/ 1 sheet (10 tablets)","offer_id":51354640384252,"sku":"2190041F1027 -1","price":2721.0,"currency_code":"JPY","in_stock":false},{"title":"50mg \/ 10 sheets (100 tablets)","offer_id":51354640417020,"sku":"2190041F1027 -2","price":21768.0,"currency_code":"JPY","in_stock":false},{"title":"100mg \/ 1 sheet (10 tablets)","offer_id":51354640449788,"sku":"2190041F2023-1","price":3978.0,"currency_code":"JPY","in_stock":false},{"title":"100mg \/ 10 sheets (100 tablets)","offer_id":51354640482556,"sku":"2190041F2023-2","price":31824.0,"currency_code":"JPY","in_stock":false},{"title":"200mg \/ 1 sheet (10 tablets)","offer_id":51354640515324,"sku":"2190041F3020-1","price":5279.0,"currency_code":"JPY","in_stock":false},{"title":"200mg \/ 10 sheets (100 tablets)","offer_id":51354640548092,"sku":"2190041F3020-2","price":42228.0,"currency_code":"JPY","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0743\/1759\/4876\/files\/50_18d1cc69-a501-4c0b-85ff-cb41c0a8c782.png?v=1789921769","url":"https:\/\/zen-pharmacy-japan.com\/products\/entresto-tablets-brand-name","provider":"ZEN PHARMACY JAPAN","version":"1.0","type":"link"}