{"product_id":"maintate-tablets-brand-name","title":"MAINTATE Tablets 0.625mg \/ 2.5mg \/ 5mg [Brand Name]","description":"\u003cdiv\u003e\n\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong\u003e\u003cem\u003eATTENTION\u003c\/em\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong\u003ePlease check countries we ship currently at the following URL \u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\u003ca href=\"https:\/\/zen-pharmacy-japan.com\/pages\/countries-we-ship-currently\" title=\"Countries we ship currently\" target=\"_blank\"\u003ehttps:\/\/zen-pharmacy-japan.com\/pages\/countries-we-ship-currently\u003c\/a\u003e\u003cbr\u003e\u003cstrong style=\"color: #0000ff;\"\u003ePlease read \"Drug Information\" for your strength before purchase.\u003c\/strong\u003e\u003cbr\u003e\u003cdiv class=\"zen-di-row\" style=\"display:flex;flex-wrap:wrap;gap:8px;margin:10px 0 14px;\"\u003e\n\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0743\/1759\/4876\/files\/MAINTATE_Tablets_0.625mg.pdf?v=1769491417\" title=\"Drug Information 0.625mg (PDF)\" rel=\"noopener\" target=\"_blank\" style=\"flex:1 1 46%;display:flex;align-items:center;justify-content:center;gap:6px;white-space:nowrap;background:#3d4fb5;color:#ffffff;font-weight:700;text-decoration:none;padding:11px 6px;border-radius:4px;font-size:13px;line-height:1.2;\"\u003e▶ Drug Information \u003cspan style=\"background:#ffffff;color:#3d4fb5;border-radius:3px;padding:1px 7px;font-size:13px;\"\u003e0.625mg\u003c\/span\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0743\/1759\/4876\/files\/MAINTATE_Tablets_2.5mg.pdf?v=1775458958\" title=\"Drug Information 2.5mg (PDF)\" rel=\"noopener\" target=\"_blank\" style=\"flex:1 1 46%;display:flex;align-items:center;justify-content:center;gap:6px;white-space:nowrap;background:#3d4fb5;color:#ffffff;font-weight:700;text-decoration:none;padding:11px 6px;border-radius:4px;font-size:13px;line-height:1.2;\"\u003e▶ Drug Information \u003cspan style=\"background:#ffffff;color:#3d4fb5;border-radius:3px;padding:1px 7px;font-size:13px;\"\u003e2.5mg\u003c\/span\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0743\/1759\/4876\/files\/MAINTATE_Tablets_5mg.pdf?v=1775531697\" title=\"Drug Information 5mg (PDF)\" rel=\"noopener\" target=\"_blank\" style=\"flex:1 1 46%;display:flex;align-items:center;justify-content:center;gap:6px;white-space:nowrap;background:#3d4fb5;color:#ffffff;font-weight:700;text-decoration:none;padding:11px 6px;border-radius:4px;font-size:13px;line-height:1.2;\"\u003e▶ Drug Information \u003cspan style=\"background:#ffffff;color:#3d4fb5;border-radius:3px;padding:1px 7px;font-size:13px;\"\u003e5mg\u003c\/span\u003e\u003c\/a\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eActive ingredient\u003c\/strong\u003e\u003cbr\u003eBisoprolol fumarate\u003cbr\u003e\u003cstrong\u003e\u003cspan style=\"color: #ff0000;\"\u003eBrand name medicine\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003eMAINTATE \u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eEffects of this medicine\u003c\/strong\u003e\u003cbr\u003e・This medicine blocks the β1-receptor, which transmits sympathetic nerve excitation to the heart, thus moderating excessive cardiac activity, resulting in antihypertensive, antianginal, antiarrhythmic, and anti-heart failure effects.\u003cbr\u003e・It is usually used to treat mild to moderate essential hypertension, angina pectoris, ventricular extrasystole, chronic heart failure (in patients receiving base treatment such as ACE inhibitors, angiotensin II receptor antagonist, diuretic, digitalis preparation) due to ischemic heart disease or dilated cardiomyopathy and tachycardiac atrial fibrillation.\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eDosing schedule (How to take this medicine)\u003c\/strong\u003e\u003cbr\u003e・For treatment of mild to moderate hypertension, angina pectoris, ventricular extrasystole: In general, for adults, take 2 tablets (5 mg of the active ingredient) at a time, once a day. The dose may be adjusted according to your disease, age and symptom. Strictly follow the instructions.\u003cbr\u003e・This product is available in 0.625mg, 2.5mg and 5mg tablets. Select the strength prescribed by your doctor from the options above.\u003cbr\u003e・For treatment of chronic heart failure:\u003cbr\u003e・�EœInitiation and dose-adjustment period�E�EIn general, for adults, initially take 0.625 mg of the active ingredient at a time, once a day. If you tolerate this medicine for 2 weeks or longer, this means you can continue to take the medicine without any problems, the dose may be increased to 1.25 mg at a time, once a day. Then if you still tolerate this medicine, the dose may be increased stepwise at intervals of at least 4 weeks. However if you no longer tolerate this medicine, the dose may be decreased. Dose increase or decrease is always stepwise, and administration is always once daily. Single dose is usually one of 0.625 mg, 1.25 mg, 2.5 mg, 3.75 mg, or 5 mg. The dosage forms of625 and 5 mg of the active ingredient, as well as 2.5 mg, and the regimen sometimes involves use of these tablets. In addition, according to your age and symptom, the initial dose may be lower than 0.625 mg\/day, and the dose increment may be less than stated above.\u003cbr\u003e・�EœMaintenance period�E�EIn general, take 1.25 to 5 mg at a time, once a day. The dose may be adjusted according to your response to this medicine, and maximum dose should not exceed 5 mg at a time, once a day. Strictly follow the instructions.\u003cbr\u003e・For treatment of tachcardiac atrial fibrillation: In general, for adults, initially take 1 tablets (2.5 mg of the active ingredient) at a time, once a day. If the effect is insufficient, the dose may be up to 2 tablets (5 mg) at a time, once a day. The dose may be adjusted according to your age and symptom, and maximum dose should not exceed 2 tablets (5 mg) at a time, once a day. Strictly follow the instructions.\u003cbr\u003e・If you miss a dose, take the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eBefore using this medicine, be sure to tell your doctor and pharmacist\u003c\/strong\u003e\u003cbr\u003e・If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods.\u003cbr\u003e・If you have bradycardia, atrioventricular block, sinoatrial block, sick sinus syndrome, diabetic ketoacidosis, metabolic acidosis, cardiogenic shock, right-sided heart failure caused by pulmonary hypertension, uncompensated heart failure, peripheral circulatory disorder, untreated pheochromocytoma.\u003cbr\u003e・If you are pregnant, possibly pregnant or breastfeeding.\u003cbr\u003e・If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003ePrecautions while taking this medicine\u003c\/strong\u003e\u003cbr\u003e・This medicine may cause dizziness or light headedness due to antihypertensive action. Be aware of driving a car or operating dangerous machinery.\u003cbr\u003e・Pay close attention to the beginning of the medication, since the medicine may show the effect strongly.\u003cbr\u003e・For healthcare professional use only\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eStorage conditions and other information\u003c\/strong\u003e\u003cbr\u003e・Keep out of reach of children. Store away from direct sunlight, heat and moisture.\u003cbr\u003e・Discard the remainder. Do not store them.\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eProduct Overview\u003c\/strong\u003e\u003cbr\u003eMAINTATE (bisoprolol fumarate) is a Japanese prescription medicine used to treat mild to moderate essential hypertension, angina pectoris, ventricular extrasystole, chronic heart failure (in patients receiving base treatment such as ACE inhibitors, angiotensin II receptor antagonist, diuretic, digitalis preparation) due to ischemic heart disease or dilated cardiomyopathy and tachycardiac atrial fibrillation. The Japanese product is manufactured under Japanese GMP and supplied in PTP sheets of 10 tablets with Japanese labeling.\u003cbr\u003e\u003cbr\u003eAvailable on this page: 0.625mg \/ 2.5mg \/ 5mg. Select the strength and quantity from the options above. All strengths are the genuine Japanese product dispensed and shipped with tracking from our licensed pharmacy in Japan.\u003cbr\u003e\u003cstrong style=\"color: #ff0000;\"\u003eFrequently Asked Questions\u003c\/strong\u003e\u003cbr\u003e\u003cb\u003eQ. What is the difference between the different strengths?\u003c\/b\u003e\u003cbr\u003eThe only difference is the amount of bisoprolol fumarate per tablet. All strengths are the same MAINTATE product with the same indication. Please choose the strength your doctor prescribed; do not change strength without medical advice.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQ. How many tablets are in one order?\u003c\/b\u003e\u003cbr\u003eOptions: 1 sheet (10 tablets) \/ 10 sheets (100 tablets).\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQ. Do I need a prescription to order?\u003c\/b\u003e\u003cbr\u003eMAINTATE is a prescription medicine in Japan. Please order only for personal use in accordance with the import regulations of your country, and consult your doctor before use.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eQ. Which countries do you ship to?\u003c\/b\u003e\u003cbr\u003ePlease see our \u003ca href=\"https:\/\/zen-pharmacy-japan.com\/pages\/countries-we-ship-currently\"\u003eshipping countries page\u003c\/a\u003e. Orders over JPY 50,000 ship free.\u003cbr\u003e\u003cbr\u003e\n\u003c\/div\u003e","brand":"ZEN PHARMACY JAPAN","offers":[{"title":"0.625mg \/ 1 sheet (10 tablets)","offer_id":51361096106236,"sku":"2123016F3037-1","price":1260.0,"currency_code":"JPY","in_stock":false},{"title":"0.625mg \/ 10 sheets (100 tablets)","offer_id":51361096139004,"sku":"2123016F3037-2","price":10080.0,"currency_code":"JPY","in_stock":false},{"title":"2.5mg \/ 1 sheet (10 tablets)","offer_id":51361096171772,"sku":"2123016F1107-1","price":1614.0,"currency_code":"JPY","in_stock":false},{"title":"2.5mg \/ 10 sheets (100 tablets)","offer_id":51361096204540,"sku":"2123016F1107-2","price":12912.0,"currency_code":"JPY","in_stock":false},{"title":"5mg \/ 1 sheet (10 tablets)","offer_id":51361096237308,"sku":"2123016F2189-1","price":2229.0,"currency_code":"JPY","in_stock":false},{"title":"5mg \/ 10 sheets (100 tablets)","offer_id":51361096270076,"sku":"2123016F2189-2","price":17832.0,"currency_code":"JPY","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0743\/1759\/4876\/files\/0625_f38021f6-5ead-4900-9a8e-63d35eb331f7.png?v=1789958075","url":"https:\/\/zen-pharmacy-japan.com\/products\/maintate-tablets-brand-name","provider":"ZEN PHARMACY JAPAN","version":"1.0","type":"link"}