ADETPHOS KOWA GRANULE 10% [Brand Name]
ADETPHOS KOWA GRANULE 10% [Brand Name]
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Please read "Drug Information" before purchase.

Product Overview
Adetphos-Kowa Granule 10% comes as a fine white granule formulation (10% ATP by weight). Adetphos-Kowa Granule 10% is a powdered/granule form of adenosine triphosphate disodium hydrate (ATP) medication, manufactured in Japan by Kowa. Like the 60 mg tablets, this formulation is used to enhance blood flow and cellular energy metabolism, thereby helping to improve symptoms such as dizziness, vertigo, and tinnitus associated with inner ear circulatory disturbances. The granule form is especially useful for patients who have difficulty swallowing pills – you can easily take it by mixing the granules in a small amount of water or juice. Each sachet of Adetphos-Kowa Granule 10% contains 1 g of granules, which provides 100 mg of ATP as the active ingredient. (The “10%” indicates that 10% of the granule’s weight is the active medicine.) This medication is commonly prescribed in Japan not only for inner ear disorders (like Meniere’s disease, which involves dizziness and ringing in the ears) but also for improving symptoms after head injuries, for certain heart conditions, chronic gastritis, and eye fatigue due to focusing difficulties. The granules are odorless and tasteless or mildly sweet (due to additives like sucrose), making them palatable and easy to ingest with water. This formulation offers the same therapeutic benefits as the enteric-coated tablets, with the difference that it can be taken dissolved, providing an alternative for those who prefer not to take tablets.
Dosage Guidelines
The dosage of Adetphos-Kowa Granule 10% will depend on the condition being treated, but the general guidelines are as follows. For inner ear disorders such as Meniere’s disease or severe vertigo, the usual adult dose is 1 g of granules (one sachet, containing 100 mg of ATP), taken three times a day. For other indications (such as improving cerebral circulation or mild symptoms), the typical dose is 0.4–0.6 g of granules (40–60 mg ATP) three times daily. Your doctor may adjust the dosage based on your specific needs. It’s recommended to dissolve the granule dose in about 50–100 ml of water and drink it, or you can place the granules on your tongue and wash them down with water. The granules dissolve easily and should be taken immediately after dissolving to ensure you get the full dose. Do not mix the granules with hot liquids (as excessive heat might potentially reduce the potency of the drug) – use room temperature or cool water. If you accidentally take more than prescribed, or take the wrong amount, contact a healthcare provider for advice. Always follow the dosing schedule provided by your physician or the product instructions. Do not abruptly change your dose or frequency without consulting a doctor.
Possible Side Effects
Because the active ingredient is the same as in the tablet form, the side effect profile for Adetphos-Kowa Granule 10% is similar. Most users do not experience significant side effects. Mild side effects that have been reported include:
- Stomach discomfort or mild diarrhea (due to increased gut activity)
- Nausea or feeling of queasiness
- Skin rash or itchiness (possible mild allergic reaction)
These side effects are typically rare and mild. If they occur, they often resolve on their own as your body adjusts. If you experience any persistent or bothersome side effects, you should stop taking the granules and consult a physician. In case of any sign of a serious reaction (which is very rare) such as severe rash, swelling, or difficulty breathing, seek medical attention immediately. Always inform your doctor of all medications and supplements you are taking, as ATP can theoretically interact with other drugs (though significant interactions with this medication are not common). Overall, Adetphos-Kowa has been used safely in a wide range of patients. Following the recommended dosage and guidelines will minimize the risk of adverse effects.
FAQ
Q: What if I have trouble taking the granules? Any tips?
A: Most people find the granules easy to take. Here are a few tips: You can dissolve the granule powder in a cup with a small amount of water (or a non-hot beverage of your choice) – it dissolves quickly. Stir and drink it immediately. If any residue remains, add a bit more water, swirl, and drink to get the full dose. The granules don’t have a strong taste (some say it’s slightly sweet/bland), so you can even take them by placing the granules directly on your tongue and then drinking water. If you experience any mild throat irritation (unlikely), make sure to use enough water. You should not mix the granules into hot drinks or carbonated drinks. Taking them with meals is usually fine and can sometimes help if you experience any mild stomach upset. Because this form doesn’t require swallowing a tablet, it’s ideal if you have a gag reflex issue with pills. If you still find it challenging, you might chill the water a bit; some find cold water helps in swallowing. Should you have any particular issue (like aftertaste or texture), please let us know – we can suggest further solutions. But generally, patients young and old handle the granule form quite well.
Q: How should I store the granule sachets once I receive them?
A: Store the Adetphos-Kowa Granule 10% sachets in a cool, dry place, away from direct sunlight – similar to storage for the tablets. Keep the sachets in their foil packets until you are ready to use them; do not open a sachet and leave it exposed to air for long, as moisture could affect the powder. If you need to only use a portion of a sachet (not typical, since usually one sachet is one dose), the remaining should be sealed tightly and used as soon as possible. Do not refrigerate or freeze the granules; room temperature (around 15–25°C or 59–77°F) is ideal. Avoid storing them in bathrooms or near kitchen sinks where humidity is high. Also, keep them out of reach of children. Each sachet is for single use – once opened, use the entire content for that dose. Check the expiration date on the sachet and try to use all sachets before that date for maximum effectiveness. Proper storage will ensure the granules remain effective until the last dose.
Q: Can I take Adetphos-Kowa Granule 10% with other medications or supplements?
A: Adenosine triphosphate (ATP) is a substance that works on metabolic pathways, and it generally has a low risk of interacting with other drugs. However, it’s always important to be cautious. If you are on other medications – especially those affecting blood pressure, heart function, or blood flow – you should consult with a doctor before using Adetphos-Kowa. No major drug interactions have been reported with ATP granules, but individual cases can vary. If you take supplements such as vitamins or herbal remedies that claim to improve circulation or energy, it’s a good idea to stagger their use apart from Adetphos (to avoid any overlap effects, even though none are specifically known). As a rule of thumb, give about a 2-hour gap between Adetphos-Kowa and other oral medications to allow each to be absorbed properly. If your doctor has provided instructions knowing you’re taking this medicine, follow their guidance. Always inform healthcare providers that you are taking Adetphos-Kowa granules if you undergo any medical treatment. They might not be familiar with the brand name if they are outside Japan, so explain it is an ATP supplement/medication for circulation. This will help them give you the best advice regarding concurrent use with other treatments.
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