ALESION Ophthalmic Solution 0.05% [Brand Name]
ALESION Ophthalmic Solution 0.05% [Brand Name]
Please check countries we ship currently at the following URL
https://zen-pharmacy-japan.com/pages/countries-we-ship-currently
Please read "Drug Information" before purchase.

Product Overview
Alesion Ophthalmic Solution 0.05% is a Japanese-made, anti-allergy eye drop formulated to relieve the symptoms of allergic conjunctivitis (eye allergies). It contains epinastine hydrochloride 0.05%, an effective antihistamine that targets itchy, red eyes caused by common allergens such as pollen (hay fever), dust mites, or pet dander. Alesion 0.05% has been a trusted treatment in Japan since its introduction in 2013, providing reliable relief for allergy-related eye irritation. (In some countries, this medication is also known by the brand name Relestat.) As the standard concentration formulation of Alesion, it typically requires four applications per day (morning, afternoon, evening, and before bed) to maintain continuous symptom relief. This well-established eye drop is manufactured in Japan under strict quality standards, ensuring you receive a safe and high-quality solution for seasonal or year-round allergic conjunctivitis.
Dosage Guidelines
The usual recommended dose of Alesion 0.05% for allergic conjunctivitis is 1 drop in each affected eye, four times daily (typically once each in the morning, afternoon, evening, and at bedtime). Try to space the doses evenly throughout the day (for example, roughly every 4–6 hours) to maintain consistent relief. Follow these steps for proper application:
- Wash your hands thoroughly before using the eye drops.
- Tilt your head back and gently pull down your lower eyelid to create a small pocket.
- Hold the bottle above the eye and squeeze one drop into the pocket of the lower eyelid, taking care not to touch your eye or eyelashes with the dropper tip.
- Close your eye and refrain from blinking for about 1-2 minutes. You can gently press the inner corner of your eye (near the nose) during this time to help the medicine stay in the eye and to prevent it from draining into the tear duct.
- Wipe away any excess liquid with a clean tissue.
Always use Alesion 0.05% as directed and do not exceed the recommended four-times-daily frequency. Using it regularly, even on days when your symptoms seem mild, will help keep allergy symptoms under control. If you are using any other eye drops, wait at least 5 minutes between applying different medications to avoid washing one out with the other. If you wear contact lenses, remove them before applying Alesion, and wait at least 10-15 minutes after using the drops before reinserting your lenses. Do not apply more than 1 drop at a time to each eye. If you accidentally apply too many drops or if someone swallows the solution, seek medical advice immediately. If you happen to miss a dose, apply it as soon as you remember unless it’s almost time for the next dose (in that case, skip the missed dose – see the FAQ below for more details).
Possible Side Effects
Alesion 0.05% is generally safe and well-tolerated, with most users experiencing no side effects or only mild, temporary ones. Possible side effects may include:
- Light stinging or a slight burning sensation in the eyes right after applying a drop
- Temporary blurred vision or minor eye redness
- Watery eyes or mild eye irritation
- Rarely, headaches or mild nasal congestion (stuffy nose)
These side effects, if they occur, typically go away on their own within minutes as your eyes adjust to the medication. Alesion 0.05% has a strong safety record; serious side effects are very uncommon. If you experience persistent burning, intense eye pain, significant swelling around the eyes, skin rash, or any signs of an allergic reaction, stop using the drops and consult a healthcare professional immediately. As long as you use the drops as directed, you are unlikely to have any serious issues. If you have any concerns about side effects, speak with your doctor or pharmacist before starting the treatment.
FAQ
Q: What should I do if I miss a dose?
A: If you forget to use Alesion 0.05% at the scheduled time, apply the missed dose as soon as you remember. If it’s almost time for your next dose when you remember, skip the missed dose and continue with your regular dosing schedule. Do not double the next dose to compensate for the missed one. Keeping to the recommended four-times-daily schedule as consistently as possible will give you the best results in managing your allergy symptoms.
Q: Can I use these eye drops while wearing contact lenses?
A: You should not instill Alesion 0.05% while wearing contact lenses. Always remove your contact lenses before applying the eye drops, and wait at least 10–15 minutes after using the drops before putting your lenses back in. This precaution prevents the medication (and its preservatives) from adhering to your lenses or causing irritation. Make sure to only apply the drops when your lenses are out, and give your eyes time to absorb the medicine before you wear contacts again.
Q: What is the difference between Alesion 0.05% and Alesion LX 0.1% eye drops?
A: The main difference is the concentration of the active ingredient and how often you need to use the drops. Alesion 0.05% is the standard-strength version and usually requires four doses per day (spread throughout the day) to keep allergy symptoms under control. Alesion LX 0.1% is a high-strength version that contains double the concentration of epinastine, allowing it to be used only twice a day (morning and evening) while still providing effective relief. In other words, Alesion LX offers longer-lasting effect per drop and the convenience of fewer daily applications, which can be beneficial for those with more severe symptoms or those who prefer not to use drops as frequently. Both versions are produced in Japan and work via the same antihistamine mechanism; they will both help relieve itchy, red allergy eyes, but the 0.1% (LX) stays effective in the eye longer than the 0.05% version, which is why the dosing schedules differ.
Q: How should I store Alesion eye drops?
A: Store Alesion 0.05% in a cool, dry place at room temperature (ideally between about 1°C and 30°C / 34°F–86°F), away from direct sunlight and moisture. Keep the bottle tightly closed when not in use, and out of reach of children and pets. Do not store the eye drops in extreme heat or freeze them. Check the expiration date on the bottle and do not use the drops if they are expired. Once you open a bottle, it’s best to use it up within about one month to ensure sterility and effectiveness, although the unopened product typically has a shelf life of a year or more. After you have finished your course of treatment (or the allergy season has passed), safely discard any remaining solution unless your doctor or pharmacist advises otherwise.
Q: Can children or pregnant women use Alesion 0.05% eye drops?
A: Alesion 0.05% is a prescription medication, so if it needs to be used by children or by women who are pregnant or breastfeeding, it should be under the supervision of a healthcare provider. If you are pregnant or nursing, consult your doctor before using these eye drops to make sure the benefits outweigh any potential risks. Likewise, for children, an eye doctor or pediatrician should be consulted to determine if this eye drop is appropriate and to provide guidance on proper usage. In practice, doctors in Japan may prescribe Alesion to children for allergy-related conjunctivitis, but the decision and dosing must be made by a medical professional. Always follow your doctor's instructions when it comes to using prescription eye drops during pregnancy or for a child.
Couldn't load pickup availability
![ALESION Ophthalmic Solution 0.05% [Brand Name] : 1 bottle (5mL)](http://zen-pharmacy-japan.com/cdn/shop/files/0.05_5d3d4286-102d-4b2a-a272-e7323d92a88d.jpg?v=1746843578&width=1445)