DENOTAS CHEWABLE CONBINATION TABLETS [Brand Name]

ATTENTION
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Please read "Drug Information" before purchase.

Active ingredient
Precipitated calcium carbonate
Cholecalciferol
Magnesium carbonate
Brand name medicine
DENOTAS
Effects of this medicine
・This medicine contains calcium, natural vitamin D3 (cholecalciferol) and magnesium carbonate. Blood calcium is engaged in actions such as neurotransmission, muscle contraction and blood coagulation. Natural Vitamin D (Vitamin D2 and D3) is metabolized in the liver to 25(OH) D and then turns into activated vitamin D [1, 25(OH)2D] in the kidney. It increases the blood calcium by promoting calcium absorption in the small intestine and enhancing calcium reabsorption in the renal tubular. Magnesium is involved in calcium metabolism.
・It is usually used to treat or prevent hypocalcemia associated with the use of RANKL inhibitors (denosumab [recombinant], etc.).
Dosing schedule (How to take this medicine)
・In general, for adults, take 2 tablets at a time, once a day. However, the dosage may be adjusted according to the age or symptoms. Strictly follow the instructions.
・This medicine is chewable. Chew or dissolve the tablet in your mouth.
・If you miss a dose, take the missed dose as soon as possible. If it is almost time for your next dose, skip the missed one dose. You should never take two doses at one time.
Before using this medicine, be sure to tell your doctor and pharmacist
・If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods.
・If you have hypercalcemia or renal disorder.
・If you are pregnant or breastfeeding.
・If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Precautions while taking this medicine
・Blood calcium may have to be measured while medication. Please follow your doctor's instructions and take a test on your designated date and time.
・Be aware that disorders such as hypercalcemia may occur when you drink a large amount of milk during medication.
・For healthcare professional use only
Storage conditions and other information
・Keep out the reach of children. Store away from light, heat and moisture.
・In case of plastic bottle, screw the cap tightly after use.
・Do not replace the contents to a different container.
・Discard the remainder. Do not store them. If you do not know how to discard the remainder, ask your pharmacist or medical institution. Do not give the medicine to anyone else.